Haïssaguerre M, Gencel L, Fischer B, Le Métayer P, Poquet F, Marcus F I, Clémenty J
Centre Hospitalier et Universitaire de Bordeaux, Hôpital Cardiologique du Haut-Lévêque, Pessac, France.
J Cardiovasc Electrophysiol. 1994 Dec;5(12):1045-52. doi: 10.1111/j.1540-8167.1994.tb01146.x.
Catheter ablation of a case of incessant atrial fibrillation was attempted using linear right atrial lesions created by sequential applications of radiofrequency energy.
A 46-year-old patient had incessant episodes of atrial fibrillation. He had previously undergone successful radiofrequency catheter ablation of a common atrial flutter. Antiarrhythmic drugs including amiodarone and various drug combinations were ineffective. A 7-French specially designed 14-polar catheter with interelectrode distance of 3 mm was used to create linear lesions in the right atrium. Each electrode was 4 mm in length and able to transmit radiofrequency energy. Three linear lesions, two longitudinal and one transverse that connected the two longitudinal lesions, were created using 30 radiofrequency applications of 10 to 40 W. The final application interrupted an atrial fibrillation that had been persistent for 55 minutes. No sustained atrial fibrillation was inducible despite repeated pacing maneuvers. There was no complication. In short-term follow-up of 3 months, the patient has been free of arrhythmias without antiarrhythmic medication.
Successful catheter ablation of human atrial fibrillation is feasible using linear atrial lesions created by radiofrequency energy delivery. Further studies are mandatory to ascertain the efficacy and safety of this procedure, as well as to assess different catheter techniques.
尝试通过连续施加射频能量形成线性右心房损伤来对一例持续性心房颤动进行导管消融。
一名46岁患者患有持续性心房颤动发作。他此前曾成功接受过常见心房扑动的射频导管消融术。包括胺碘酮及各种药物组合在内的抗心律失常药物均无效。使用一根专门设计的7F 14极导管,电极间距为3mm,在右心房形成线性损伤。每个电极长度为4mm,能够传输射频能量。通过30次10至40W的射频应用,形成了三条线性损伤,两条纵向损伤以及一条连接两条纵向损伤的横向损伤。最后一次应用终止了持续55分钟的心房颤动。尽管反复进行起搏操作,仍无法诱发持续性心房颤动。未出现并发症。在3个月的短期随访中,患者未服用抗心律失常药物,未发生心律失常。
使用通过射频能量传递形成的线性心房损伤成功进行人类心房颤动导管消融是可行的。必须进一步开展研究以确定该手术的疗效和安全性,以及评估不同的导管技术。