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Immunodeficiency. Trapping the nude mouse gene. - Suppr | 超能文献

Immunodeficiency. Trapping the nude mouse gene.

作者信息

Reth M

机构信息

Department of Molecular Immunology, Max-Planck Institut für Immunbiologie, Freiburg, Germany.

出版信息

Curr Biol. 1995 Jan 1;5(1):18-20. doi: 10.1016/s0960-9822(95)00006-6.

DOI:10.1016/s0960-9822(95)00006-6

Abstract

Hairless nude mice are immunodeficient because they lack a thymus. The nude gene has now been identified; it encodes a winged-helix transcription factor that is expressed specifically in skin and thymus.

摘要

相似文献

1

Immunodeficiency. Trapping the nude mouse gene.

Curr Biol. 1995 Jan 1;5(1):18-20. doi: 10.1016/s0960-9822(95)00006-6.

2

New member of the winged-helix protein family disrupted in mouse and rat nude mutations.在小鼠和大鼠裸突变中被破坏的翼状螺旋蛋白家族新成员。

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The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation.

Genes Dev. 1996 Sep 1;10(17):2212-21. doi: 10.1101/gad.10.17.2212.

4

Ectopic expression of the nude gene induces hyperproliferation and defects in differentiation: implications for the self-renewal of cutaneous epithelia.裸基因的异位表达诱导过度增殖和分化缺陷：对皮肤上皮自我更新的影响。

Dev Biol. 1999 Aug 1;212(1):54-67. doi: 10.1006/dbio.1999.9328.

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Exposing the human nude phenotype.揭示人类裸体表型。

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The nude gene encodes a sequence-specific DNA binding protein with homologs in organisms that lack an anticipatory immune system.裸基因编码一种序列特异性DNA结合蛋白，在缺乏预期免疫系统的生物体中存在同源物。

Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3842-7. doi: 10.1073/pnas.94.8.3842.

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Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.

Eur J Immunol. 2001 Aug;31(8):2497-503. doi: 10.1002/1521-4141(200108)31:8<2497::aid-immu2497>3.0.co;2-j.

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Positional cloning of the nude locus: genetic, physical, and transcription maps of the region and mutations in the mouse and rat.

Genomics. 1995 Aug 10;28(3):549-59. doi: 10.1006/geno.1995.1187.

引用本文的文献

1

The thymus of the hairless rhino-j (hr/rh-j) mice.无毛犀牛-j（hr/rh-j）小鼠的胸腺。

J Anat. 2001 Apr;198(Pt 4):399-406. doi: 10.1046/j.1469-7580.2001.19840399.x.

2

Essential defects of athymic nude mice affect also the nu/+ heterozygotes.

Folia Microbiol (Praha). 1998;43(5):491-2. doi: 10.1007/BF02820800.