Weber D O, Gooch J J, Wood W R, Britt E M, Kraft R O
Arch Surg. 1976 Apr;111(4):484-8. doi: 10.1001/archsurg.1976.01360220180031.
The influence of operating room contamination on wound infection rates in clean, clean-contaminated, contaminated, and septid procedures was studied by a prospective randomized study of 2,020 surgical wounds. Operating room surface contamination was assessed by the RODAC bacterial plate method. Control rooms uniformly received Wet-Vac cleaning between operations. Experimental rooms were not cleaned between consecutive clean operations, but were cleaned after contaminated operations. The difference in surface contamination between groups of experimental and control rooms was found to be significant at the P less than .05 level. Patients operated on in experimental and control rooms were followed up postoperatively to assess whether they experienced wound infection. No statistically significant differences in wound infection rates were found between experimental and control room operations as total groups, clean procedures, or operations of long duration.
通过对2020例手术伤口进行前瞻性随机研究，探讨手术室污染对清洁、清洁-污染、污染及感染手术伤口感染率的影响。采用RODAC细菌平板法评估手术室表面污染情况。对照组手术室在手术之间统一采用湿真空清洁法。试验组手术室在连续的清洁手术后不进行清洁，但在污染手术后进行清洁。试验组和对照组手术室之间的表面污染差异在P值小于0.05水平时具有统计学意义。对在试验组和对照组手术室接受手术的患者进行术后随访，以评估他们是否发生伤口感染。在试验组和对照组手术室进行的所有手术、清洁手术或长时间手术中，伤口感染率均未发现有统计学意义的差异。
