Synthesis of 9E- and 9Z-locked retinoic acid analogs as ligands for RAR and RXR.
作者信息
Katsuta Y, Aoyama Y, Osone H, Wada A, Uchiyama S, Kitamoto T, Masushige S, Kato S, Ito M
机构信息
Kobe Pharmaceutical University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1994 Dec;42(12):2659-61. doi: 10.1248/cpb.42.2659.
PMID:7697779
Abstract
New retinoic acid (RA) analogs 9E-locked-RA 3 and 9Z-locked-RA 4 were synthesized from dithiane 6 and beta-cyclocitral 13, respectively. Both analogs behaved as agonistic ligands for a mixture of retinoic acid receptor (RAR) and retinoid X receptor (RXR).
摘要
Zotero 插件