High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene.

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作者信息

Wislocki P G, Wood A W, Chang R L, Levin W, Yagi H, Hernandez O, Jerina D M, Conney A H

出版信息

Biochem Biophys Res Commun. 1976 Feb 9;68(3):1006-12. doi: 10.1016/0006-291x(76)91246-8.

DOI:10.1016/0006-291x(76)91246-8

PMID:769789

Abstract

摘要

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High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene.

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Specificity in interaction of benzo[a]pyrene with nuclear macromolecules: implication of derivatives of two dihydrodiols in protein binding.苯并[a]芘与核大分子相互作用的特异性：两种二氢二醇衍生物在蛋白质结合中的意义。

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