氟氢可的松治疗糖尿病性体位性低血压的经验
Therapeutic experience with fludrocortisone in diabetic postural hypotension.
作者信息
Campbell I W, Ewing D J, Clarke B F
出版信息
Br Med J. 1976 Apr 10;1(6014):872-4. doi: 10.1136/bmj.1.6014.872.
Abstract
Fourteen patients with diabetic postural hypotension were treated with fludrocortisone for a mean 12 months (range 6-30 months). The mean daily dose of fludrocortisone was 0.2 mg (range 0.1 mg-0.4 mg). Standing systolic and diastolic blood pressures increased significantly (P less than 0.001) after treatment with fludrocortisone and the postural hypotension decreased significantly (P less than 0.001). Thirteen patients noted considerable symptomatic improvement. Fludrocortisone should be used cautiously in patients with congestive cardiac failure or the nephrotic syndrome.
摘要
14例糖尿病性体位性低血压患者接受氟氢可的松治疗，平均治疗12个月（范围6 - 30个月）。氟氢可的松的平均日剂量为0.2毫克（范围0.1毫克 - 0.4毫克）。使用氟氢可的松治疗后，站立位收缩压和舒张压显著升高（P < 0.001），体位性低血压显著降低（P < 0.001）。13例患者症状有明显改善。充血性心力衰竭或肾病综合征患者应谨慎使用氟氢可的松。
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