Allègre G, Avrillier S, Albe-Fessard D
EPHE, Hôpital Paul Guiraud, Villejuif, France.
Neurosci Lett. 1994 Oct 24;180(2):261-4. doi: 10.1016/0304-3940(94)90534-7.
A bundle of central nervous fibers was excited in the rat with a short pulse (40 ns) of UV light produced by an excimer laser. Evoked responses were recorded in the thalamic ventralis posterior nucleus after stimulation of the medial lemniscus or the cuneate bundle in the spinal cord. The effects of electrical and optical fiber applied UV stimulation were compared in both cases. At threshold, the latency for the UV light stimulation was slightly longer than for electrical stimulation. The excitation threshold was 0.9 J/cm2, very close to the UV photoablation threshold (order of 1 J/cm2). The intermediary events mediating the light excitation are discussed.
用准分子激光产生的短脉冲（40纳秒）紫外光刺激大鼠的一束中枢神经纤维。刺激脊髓中的内侧丘系或楔束后，在丘脑腹后核记录诱发反应。在这两种情况下，比较了电刺激和光纤施加的紫外线刺激的效果。在阈值时，紫外线刺激的潜伏期略长于电刺激。激发阈值为0.9 J/cm²，非常接近紫外线光消融阈值（约1 J/cm²）。讨论了介导光激发的中间事件。
