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帕金森症的治疗。

Treatment of parkinsonism.

作者信息

Selby G

出版信息

Drugs. 1976;11(1):61-70. doi: 10.2165/00003495-197611010-00006.

Abstract

Although the mortality of Parkinsonism is negligible, it is one of the major causes of progressive and often pitiful disability in the elderly. Treatment of the condition, whether medical or surgical, is still only palliative. The successes and limitations of the various forms of treatment are discussed. Despite the spectacular gains which have been achieved during the past 25 years by sterotactic thalamotomy and treatment with levodopa, the patient's disabilities tend to progress slowly and the fundamental enigma of Parkinson's disease and of its cure still awaits solution.

摘要

尽管帕金森症的死亡率可以忽略不计,但它却是老年人渐进性且常常令人可怜的残疾的主要原因之一。该病症的治疗,无论是药物治疗还是手术治疗,仍然只是姑息性的。文中讨论了各种治疗方式的成效与局限性。尽管在过去25年里,立体定向丘脑切开术和左旋多巴治疗取得了显著进展,但患者的残疾往往仍会缓慢进展,帕金森病及其治愈方法的根本谜团仍有待解决。

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