Bøhmer T
Medisinsk avdeling, Aker sykehus, Oslo.
Tidsskr Nor Laegeforen. 1995 Mar 10;115(7):827-8.
Magnesium participates in a number of biochemical reactions that seem to be important when lung function is disturbed. A low intake of magnesium in the diet increases bronchial reactivity. Magnesium supplementation reduces bronchial constriction and pressure in pulmonary hypertension, and increases the force of the respiratory muscles. In experimental animals, magnesium supplementation prevents lung changes precipitated by acoustic trauma. These changes are similar to the adult respiratory distress syndrome in humans. Theofylline, an important drug in the treatment of severe bronchial asthma, increases urinary loss of magnesium. A number of the patients in the intensive care unit have magnesium deficiency. Therefore it appears that some of the lung patients would benefit from treatment with magnesium.
镁参与许多生化反应,当肺功能受到干扰时,这些反应似乎很重要。饮食中镁摄入量低会增加支气管反应性。补充镁可减轻支气管收缩和肺动脉高压中的压力,并增加呼吸肌的力量。在实验动物中,补充镁可预防因声学创伤引起的肺部变化。这些变化类似于人类的成人呼吸窘迫综合征。茶碱是治疗严重支气管哮喘的一种重要药物,会增加镁的尿排泄量。重症监护病房的许多患者存在镁缺乏。因此,似乎一些肺部疾病患者会从镁治疗中受益。