牛3号染色体的遗传和物理图谱。

A genetic and physical map of bovine chromosome 3.

作者信息

Vaiman D, Eggen A, Mercier D, Bahri-Darwich I, Grohs C, Bruneau D, Laurent P, Chaput B, Oustry A, Frelat G

机构信息

Laboratoire de Génétique biochimique et de Cytogénétique, INRA-CRJ, Jouy-en-Josas, France.

出版信息

Anim Genet. 1995 Feb;26(1):21-5. doi: 10.1111/j.1365-2052.1995.tb02614.x.

DOI:10.1111/j.1365-2052.1995.tb02614.x

PMID:7702208

Abstract

This paper reports a map of nine polymorphic microsatellite markers previously assigned to bovine chromosome 3 (BTA3) by somatic cell genetics. The linkage group covers 101 cM on the chromosome with an average intermarker distance of 13.9 cM. One marker (INRA200) was isolated from a peak of flow sorted chromosomes 2 and 3. Another marker (INRA197) was derived from a cosmid. The localization of the cosmid by in situ hybridization enabled the orientation of the linkage group on BTA3. Markers were relatively evenly spaced and consequently can be used to complement other mapping data about this chromosome. This establishes a framework of polymorphic markers that can be used to search for quantitative trait loci (QTL).

摘要

本文报道了一张由体细胞遗传学先前定位到牛3号染色体（BTA3）上的9个多态微卫星标记图谱。该连锁群覆盖染色体上101厘摩的区域，标记间平均间距为13.9厘摩。一个标记（INRA200）是从流式分选的2号和3号染色体峰中分离出来的。另一个标记（INRA197）来源于一个黏粒。通过原位杂交对黏粒进行定位，确定了该连锁群在BTA3上的方向。标记相对均匀分布，因此可用于补充有关该染色体的其他图谱数据。这建立了一个多态标记框架，可用于寻找数量性状基因座（QTL）。