黏粒CSSM25将同线群U2定位于牛的9号染色体，并定位于绵羊的8号染色体。

The cosmid CSSM25 assigns syntenic group U2 to bovine chromosome 9 and is localized to ovine chromosome 8.

作者信息

Johnson S E, Moore S S, MacKinnon R, Hetzel D J, Barendse W

机构信息

CSIRO, Division of Tropical Animal Production, University of Queensland-St Lucia, Brisbane, Australia.

出版信息

Mamm Genome. 1995 Aug;6(8):529-31. doi: 10.1007/BF00356170.

DOI:10.1007/BF00356170

PMID:8589522

Abstract

The cosmid-derived microsatellite CSSM 25 has previously been shown to map to bovine syntenic group U2 by linkage and hybrid somatic cell analysis. We have mapped the cosmid by fluorescent in situ hybridization to bovine Chromosome (Chr) 9q17-21 and ovine Chr 8q17-21 and hence assign U2 to Chr 9 in cattle. Bovine Chr 9 and ovine Chr 8 show strong banding pattern homology, and the localization of CSSM 25 to the same region confirms the strong conservation of gene locations on these chromosomes.

摘要

先前已通过连锁分析和杂交体细胞分析表明，黏粒衍生的微卫星CSSM 25定位于牛的同线群U2。我们通过荧光原位杂交将该黏粒定位于牛染色体（Chr）9q17 - 21和绵羊Chr 8q17 - 21，因此在牛中将U2定位于Chr 9。牛Chr 9和绵羊Chr 8显示出很强的带型同源性，并且CSSM 25定位于相同区域证实了这些染色体上基因位置的高度保守性。