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[穿掘性毛囊周围炎。异维A酸的疗效]

[Perifolliculitis capitis abscedens and suffidiens. Efficacy of isotretinoin].

作者信息

Dubost-Brama A, Delaporte E, Alfandari S, Piette F, Bergoend H

机构信息

Service de Dermatologie A, Hôpital Claude-Huriez, CHRU, Lille.

出版信息

Ann Dermatol Venereol. 1994;121(4):328-30.

PMID:7702254
Abstract

Perifolliculitis capitis abscedens et suffodiens is a rare, chronic and suppurative scalp disease. The treatment of this condition is difficult. CASE REPORT. We report a case successfully treated with isotretinoin at the dose of 2/3 mg/kg/day during eight month. DISCUSSION. The main difficulty is the maintenance of remission after drug withdrawal, so, duration of treatment has to be defined. A eight month's therapy seems to constitute the minimum duration in this pathology. A second course of isotretinoin is still possible if relapse occurs. CONCLUSION. A long course of isotretinoin can be considered as the most effective treatment in perifolliculitis capitis abscedens et suffodiens.

摘要

穿掘性头部毛囊周围炎是一种罕见的慢性化脓性头皮疾病。这种病症的治疗很困难。病例报告。我们报告一例患者,以2/3毫克/千克/天的剂量服用异维A酸治疗八个月后成功治愈。讨论。主要困难在于停药后维持缓解状态,因此必须确定治疗时长。八个月的治疗似乎是这种病症的最短治疗时长。如果复发,仍可进行第二个疗程的异维A酸治疗。结论。可以认为长疗程的异维A酸治疗是穿掘性头部毛囊周围炎最有效的治疗方法。

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