Cousin M T, Pipien I, Bergaoui F, Massonnet-Castel S, Fabiani J N
Service d'Anesthésie-Réanimation, Hôpital Broussais, Paris.
Ann Chir. 1994;48(9):818-24.
To verify that the rate of post operative infections is higher with homologous transfusion rather than without, 86 coronary artery bypass patient charts were retrospectively studied. Inclusion criteria were those of the autologous transfusion group. Four groups were defined : Gr 1 : No transfusion. Gr 2: Autotransfusion. Gr 3: Allotransfusion. Gr 4: Autotransfusion who also received homologous blood products. Although not significant, the bacterial infection rate was twofold higher in the Gr 3, than in the autologous group and was almost four times higher and significant (p < 0.01) when patients who received homologous blood products were compared to those who did not. These preliminary results lead us to enlarge our autotransfusion program and us encourage, to search for the cause of the decreased infection rate after autologous transfusion by prospective studies.
为了验证同种输血患者术后感染率是否高于未输血患者,我们回顾性研究了86例冠状动脉搭桥患者的病历。纳入标准与自体输血组相同。我们定义了四组:第1组:未输血。第2组:自体输血。第3组:同种输血。第4组:自体输血且同时接受同种血液制品。虽然差异不显著,但第3组的细菌感染率是自体输血组的两倍,而接受同种血液制品的患者与未接受者相比,感染率几乎高出四倍且具有显著性差异(p < 0.01)。这些初步结果促使我们扩大自体输血计划,并鼓励我们通过前瞻性研究寻找自体输血后感染率降低的原因。