Ferrari E, Drai E, Taillan B, Talbodec A, Baudouy M, Morand P
Service de Cardiologie, Hôpital Pasteur, Nice.
Ann Cardiol Angeiol (Paris). 1995 Jan;44(1):14-5.
The authors report a case of severe pulmonary hypertension (PHT) in a couple of HIV seropositive heroin addicts. The parallel clinical course in these two patients with only mild immunodeficiency and the fact that they both had the same supplier were in favour of PHT secondary to talcoma. In the light of these cases, one wonders whether, as suggested by certain epidemiological studies currently underway, drug addiction should be considered to be a cause of PHT in its own right. According to the authors, this approach would underestimate the incidence of this disease in this particular population and would therefore bias the epidemiological data.
作者报告了一对感染艾滋病毒且吸食海洛因的患者出现严重肺动脉高压（PHT）的病例。这两名患者仅有轻度免疫缺陷，临床病程相似，且他们有同一个毒品供应商，这些情况表明其肺动脉高压是由滑石粉引起的继发性病变。鉴于这些病例，有人不禁要问，正如目前正在进行的某些流行病学研究所暗示的那样，药物成瘾本身是否应被视为肺动脉高压的一个病因。作者认为，这种观点会低估该特定人群中这种疾病的发病率，从而使流行病学数据产生偏差。
