Ozkirimli S, Hamali O
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.
Farmaco. 1995 Jan;50(1):65-7.
Several 1-Substituted benzylideneamino-2-thioxo-4,5-imidazolidinedione derivatives were synthesized 2a-i, characterized and evaluated for hypnotic activity. The tested compounds increased the sleeping time to a significant value (p < 0.001).
合成了几种1-取代亚苄基氨基-2-硫代-4,5-咪唑啉二酮衍生物2a-i,对其进行了表征并评估了催眠活性。测试的化合物使睡眠时间显著增加(p < 0.001)。