Mahé M, Chatal J F
Service de radiothérapie, site hospitalier Nord de Nantes-Saint-Herblain, bd Jacques-Monod, France.
Bull Cancer. 1994 Sep;81(9):788-99.
Radioimmunotherapy is a special form of internal radiotherapy which uses radiolabeled monoclonal antibodies. Until now, best results were achieved in refractory lymphomas and in ovarian cancer with minimal tumor residues. Several approaches are now under investigation to enhance tumor uptake and to improve hematologic tolerance. Recent advances in radiobiology are helpful to select future indications of this new method of treatment.
放射免疫疗法是一种特殊形式的内照射放疗,它使用放射性标记的单克隆抗体。到目前为止,难治性淋巴瘤和肿瘤残留极少的卵巢癌取得了最佳疗效。目前正在研究几种方法以提高肿瘤摄取并改善血液学耐受性。放射生物学的最新进展有助于选择这种新治疗方法未来的适应症。