Hansson J, Ringborg U, Lagerlöf B, Afzelius L E, Augustsson I, Blomquist E, Boeryd B, Carlin E, Edström S, Eldh J
Department of General Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
Melanoma Res. 1994 Dec;4(6):407-11. doi: 10.1097/00008390-199412000-00011.
The effect of elective lymph node dissection in patients with cutaneous malignant melanoma of the head and neck was investigated in a retrospective study. Of 517 patients in clinical stage I, 84 underwent elective dissection of the ipsilateral neck lymph nodes. In six of these patients, lymph node metastases were demonstrated at histopathological examination. There was a slight reduction in the incidence of recurrent disease in the regional lymph nodes in the group of patients who had undergone elective lymph node dissection, but this difference was not statistically significant. No significant differences were seen between the two groups regarding overall survival of disease-related survival.
在一项回顾性研究中,对头部和颈部皮肤恶性黑色素瘤患者进行选择性淋巴结清扫的效果进行了调查。在517例临床I期患者中,84例接受了同侧颈部淋巴结的选择性清扫。在其中6例患者中,组织病理学检查显示有淋巴结转移。接受选择性淋巴结清扫的患者组区域淋巴结复发疾病的发生率略有降低,但这种差异无统计学意义。两组在总生存率或疾病相关生存率方面均未观察到显著差异。