Laurenzo J F, Graham S M
University of Iowa Hospitals and Clinics, Department of Otolaryngology, Iowa City 52242.
Ear Nose Throat J. 1995 Feb;74(2):87-91, 94.
Tumefactive fibroinflammatory lesions are rare, benign, fibrosclerosing masses in the head and neck that appear clinically as malignancies. Twenty-one cases have been described since first reported in 1975. While all authors agree on the lesion's histopathologic characteristics, multiple variations in appearance, treatment, and results have been reported. We review a case and compile all previously reported cases. Common sites of involvement were sinonasal tract (41%), neck (37%), and parotid (23%). Symptoms frequently reported were pain (50%) and hard mass (55%). Five patients (23%) eventually developed extra-head and neck fibrosclerosing lesions. Treatments have included surgery, radiation, and corticosteroids, occasionally in combination. Results have varied depending on size and location of lesion. Based on this review, a discussion of this rare disease and recommendations regarding diagnosis and treatment are given.
肿块性纤维炎性病变是头颈部罕见的良性纤维硬化性肿块，临床上表现为恶性肿瘤。自1975年首次报道以来，已描述了21例病例。虽然所有作者对该病变的组织病理学特征达成共识，但在外观、治疗和结果方面已报道了多种差异。我们回顾了1例病例并汇总了所有先前报道的病例。常见受累部位为鼻窦道（41%）、颈部（37%）和腮腺（23%）。经常报道的症状为疼痛（50%）和硬性肿块（55%）。5例患者（23%）最终出现头颈部以外的纤维硬化性病变。治疗方法包括手术、放疗和皮质类固醇，偶尔联合使用。结果因病变的大小和位置而异。基于本综述，对这种罕见疾病进行了讨论并给出了关于诊断和治疗的建议。
