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三例子宫内膜鳞状细胞癌新病例报告,重点关注人乳头瘤病毒(HPV)状态。

Report of three new cases of squamous carcinoma of the endometrium with emphasis in the HPV status.

作者信息

Im D D, Shah K V, Rosenshein N B

机构信息

Division of Gynecologic Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.

出版信息

Gynecol Oncol. 1995 Mar;56(3):464-9. doi: 10.1006/gyno.1995.1084.

Abstract

Primary squamous cell carcinoma of the endometrium is exceedingly rare. Only 31 cases that fulfill Fluhmann's criteria have been reported in the literature. We report three cases of primary squamous cell carcinoma of the endometrium. In two of the three cases, estrogen receptor (ER) and progesterone receptor (PR) status were analyzed. Only one case contained ER/PR. Additionally, in situ hybridization was performed to determine the presence of human papillomavirus (HPV) in these cases. HPV was not detected in these three cases of primary squamous cell carcinoma of the endometrium.

摘要

子宫内膜原发性鳞状细胞癌极为罕见。文献中仅报道了31例符合弗卢曼标准的病例。我们报告3例子宫内膜原发性鳞状细胞癌。在这3例中的2例中,分析了雌激素受体(ER)和孕激素受体(PR)状态。仅1例含有ER/PR。此外,进行了原位杂交以确定这些病例中人类乳头瘤病毒(HPV)的存在情况。在这3例子宫内膜原发性鳞状细胞癌病例中未检测到HPV。

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