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两例复发性外阴佩吉特病在中厚皮片移植中的报告及其可能的发病机制——标记为“逆行播散”

A report of two cases of recurrent Paget's disease of the vulva in a split-thickness graft and its possible pathogenesis-labeled "retrodissemination".

作者信息

DiSaia P J, Dorion G E, Cappuccini F, Carpenter P M

机构信息

Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange 92668, USA.

出版信息

Gynecol Oncol. 1995 Apr;57(1):109-12. doi: 10.1006/gyno.1995.1106.

Abstract

Two cases of recurrent noninvasive Paget's disease of the vulva in a split-thickness graft without an underlying adenocarcinoma are presented. This is the third report of recurrence of extramammary Paget's disease in a split-thickness graft, and the second of such an occurrence without an underlying dermal adnexa adenocarcinoma. A hypothesis for the possible pathogenetic mechanism of this unusual biological behavior is suggested.

摘要

本文报告了两例复发性非侵袭性外阴佩吉特病,病变位于无潜在腺癌的中厚皮片。这是乳腺外佩吉特病在中厚皮片中复发的第三例报告,也是第二例无潜在真皮附属器腺癌的此类病例。本文提出了这种异常生物学行为可能的发病机制假说。

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