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[用于运动控制的小脑-大脑环路——从小脑到大脑皮层的输出系统]

[Cerebello-cerebral loop for motor control--output systems from the cerebellum to the cerebral cortex].

作者信息

Shinoda Y

机构信息

Department of Physiology, School of Medicine, Tokyo Medical and Dental University, Japan.

出版信息

Hokkaido Igaku Zasshi. 1994 Nov;69(6):1372-81.

PMID:7705749
Abstract

Input-output organization of the ventrolateral nucleus (VL) of the thalamus was analyzed electrophysiologically and morphologically at the single cell level. Virtually all pyramidal tract neurons in the motor cortex and area 6 received convergent inputs from the dentate (DN) and the interpositus (IN) nuclei and about 60% of thalamocortical (TC) neurons received convergent inputs from both the DN and the IN. Anterograde labelling following focal injection of Phaseolus vulgaris leukoagglutinin and intracellular staining of TC axons showed that the terminals in layer III tended to aggregate into patches about 1-1.5 mm wide in a frontal plane, which were arranged in longitudinal strips about 2-5 mm long in a rostrocaudal direction.

摘要

在单细胞水平上,用电生理学和形态学方法分析了丘脑腹外侧核(VL)的输入-输出组织。实际上,运动皮层和6区的所有锥体束神经元都接受来自齿状核(DN)和间位核(IN)的汇聚输入,约60%的丘脑皮质(TC)神经元接受来自DN和IN的汇聚输入。在局部注射菜豆白细胞凝集素后进行的顺行标记以及TC轴突的细胞内染色显示,Ⅲ层中的终末在额平面上倾向于聚集成宽约1-1.5毫米的斑块,这些斑块在 rostrocaudal 方向上排列成长约2-5毫米的纵向条带。

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