Dreinhöfer K E, Rydholm A, Bauer H C, Kreicbergs A
University Hospital, Lund, Sweden.
J Bone Joint Surg Br. 1995 Mar;77(2):189-93.
Between 1971 and 1991 we treated 98 patients with giant-cell tumours, 15 of whom presented with a pathological fracture. They were most common around the knee (12). Nine fractures were intra-articular. The tumours were treated by curettage and acrylic cementing (10), excision and endoprosthesis (1), excision and allograft (1), curettage and autologous graft (2) or by resection of the fibular head (1). Four patients had local recurrence, three of whom were cured by repeat curettage and cementing. Pathological fracture through a giant-cell tumour is not a contraindication to treatment by curettage and acrylic cementing.
1971年至1991年间，我们治疗了98例骨巨细胞瘤患者，其中15例出现病理性骨折。骨折最常发生在膝关节周围（12例）。9例骨折为关节内骨折。肿瘤的治疗方法包括刮除加骨水泥填充（10例）、切除加人工关节置换（1例）、切除加同种异体骨移植（1例）、刮除加自体骨移植（2例）或腓骨头切除（1例）。4例患者出现局部复发，其中3例通过再次刮除加骨水泥填充治愈。骨巨细胞瘤导致的病理性骨折并非刮除加骨水泥填充治疗的禁忌证。
