Kumar A, Sharma V P, Sumodan P K, Thavaselvam D, Kamat R H
Malaria Research Centre (ICMR), Goa, India.
J Am Mosq Control Assoc. 1994 Dec;10(4):534-9.
In a large malaria endemic area in Panaji city, Goa, India, the weekly application of the biolarvicide Bacillus sphaericus (Strain 101, Serotype H 5a 5b) at the rate of 1 g/m2 in the main Anopheles stephensi larval habitats, viz., curing waters, masonry tanks, and sump tanks (under construction), from April to December 1993 resulted in a sharp decline in the habitat positivity (range 0.13-8.0%) as compared with the rest of the Panaji (range 2.2-30.6%) where temephos (Abate) was used as the larvicide. Bacillus sphaericus spraying also led to a significant decline in anopheline densities in positive habitats (range 0-7.3/10 dips) as compared with control habitats (range 0.9-53.0/10 dips). Concurrently, malaria incidence observed in the experimental area (slide positivity rate [SPR] range 2.3-7.8%; monthly parasite index [MPI] range 0.18-1.44) was lower than in the control area (SPR range 14.3-25.5%; MPI range 1.75-6.12).
在印度果阿邦帕纳吉市一个疟疾高发的大区域，1993年4月至12月期间，在主要的斯氏按蚊幼虫栖息地，即疗养用水区、砖石水箱和在建集水箱中，以1克/平方米的剂量每周施用生物杀幼虫剂球形芽孢杆菌（菌株101，血清型H 5a 5b），与帕纳吉市其他使用双硫磷（杀螟松）作为杀幼虫剂的区域相比，栖息地阳性率急剧下降（范围为0.13 - 8.0%）。与对照栖息地（范围为0.9 - 53.0/10次蘸取）相比，喷洒球形芽孢杆菌还导致阳性栖息地中按蚊密度显著下降（范围为0 - 7.3/10次蘸取）。同时，在试验区观察到的疟疾发病率（玻片阳性率[SPR]范围为2.3 - 7.8%；月寄生虫指数[MPI]范围为0.18 - 1.44）低于对照区（SPR范围为14.3 - 25.5%；MPI范围为1.75 - 6.12）。
