Joubert E, Idir A B, Carlier R, Belal N, Hurth M, Lacroix-Ciaudo C, Ducot B, Doyon D
Services de Neuroradiologie, Hôpital de Bicêtre, Le Kremlin-Bicêtre.
J Neuroradiol. 1995 Mar;22(1):28-42.
MRI has now been recognized as the best technique for exploration of spinal tumours and, in particular, tumours within the spinal cord. Based on a retrospective study of 74 operated glial tumours, we are trying to define a specific semiology for intramedullary astrocytomas and ependymomas. Thirty-four cases were selected including 17 astrocytomas (7 low-grade, 10 high-grade) and 17 ependymomas (1 of which was grade III) for whom the pre-operative MRI examination was complete, with T1-weighted sequences without, then with gadolinium, and T2-weighted sequences. The examination was performed using a high-field and in most cases 1.5 Tesla machine. Analysis, correlated with operative data and pathology results, comprised on the one hand patients' distribution by age, sex and location of the tumour on the spinal cord, and on the other hand the MRI semiology concerning the sagittal and axial localization of the fleshy portion after gadolinium injection, the limits of the tumour, the homo- or heterogeneous character of its enhancement, the possible existence of stigmas of intra- or peritumoral chronic bleeding, and finally the presence or absence of associated cysts in the 34 exploitable cases. Some semiological differences were elicited between astrocytomas and ependymomas: the patient's age at the time of diagnosis was predominantly 0 to 20 for astrocytomas (astrocytomas 39%, ependymomas 4%), and the well-limited character of the fleshy portion of the tumour after gadolinium injection was found in 70% of ependymomas, 40% of high-grade astrocytomas and 14% of low-grade astrocytomas. The homogeneity of contrast enhancement in ependymomas has been classically defined, but it did not show in our series. Finally, it seems that high-grade astrocytomas are characterized by the rare presence of hemosiderin deposits (high-grade 20%, low-grade 57%, ependymomas 58%) and by the absence or reduced extension of overlying and underlying cysts.
磁共振成像(MRI)现已被公认为是探查脊柱肿瘤,尤其是脊髓内肿瘤的最佳技术。基于对74例接受手术的神经胶质瘤的回顾性研究,我们试图为髓内星形细胞瘤和室管膜瘤确定一种特定的影像学特征。选取了34例病例,包括17例星形细胞瘤(7例低级别,10例高级别)和17例室管膜瘤(其中1例为Ⅲ级),这些病例的术前MRI检查完整,包括无钆剂的T1加权序列、之后有钆剂的T1加权序列以及T2加权序列。检查使用高场强,大多数情况下使用1.5特斯拉的机器。分析与手术数据和病理结果相关,一方面包括患者按年龄、性别和肿瘤在脊髓上的位置分布,另一方面包括钆剂注射后肿瘤实体部分在矢状位和轴位的定位、肿瘤边界、强化的均匀或不均匀特征、肿瘤内或肿瘤周围慢性出血的可能迹象,最后是34例可分析病例中是否存在相关囊肿。在星形细胞瘤和室管膜瘤之间发现了一些影像学差异:星形细胞瘤诊断时患者年龄多在0至20岁(星形细胞瘤占39%,室管膜瘤占4%),钆剂注射后肿瘤实体部分边界清晰的特征在70%的室管膜瘤、40%的高级别星形细胞瘤和14%的低级别星形细胞瘤中可见。室管膜瘤对比增强的均匀性已有经典定义,但在我们的系列研究中未显示。最后,似乎高级别星形细胞瘤的特征是罕见的含铁血黄素沉积(高级别占20%,低级别占57%,室管膜瘤占58%)以及上覆和下伏囊肿的缺失或范围缩小。