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[髓内胶质瘤。术后磁共振成像表现]

[Intramedullary glioma. Postoperative MRI aspects].

作者信息

Borocco A, Idir A, Joubert E, Lacroix C, Hurth M, Doyon D

机构信息

Service de Neuroradiologie, CIERM - CHU Bicêtre, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre.

出版信息

J Neuroradiol. 1995 Jun;22(2):123-30.

PMID:7629570
Abstract

MRI is the standard exploration of intramedullary tumours. Following up the patients is of prime importance to detect and treat possible recurrences at an early stage. The purpose of this paper is to specify the postoperative MRI semiology of intraspinal gliomas. During the 1986-1992 period, 47 patients operated upon in the Bicêtre hospital for primary intraspinal tumours were followed up with high-field MR (1.5 Tesla, Signa, G.E.). The retrospective visual study was carried out by two neuro-radiologists. The patients' group consisted of 24 women and 23 men aged from 15 to 67 years (mean 38 years). The tumours treated were 29 ependymomas and 18 astrocytomas. Eighty-five MRI examinations were analysed. Most of them comprised at least two planes in T1 and T2-weighted spin echo sequences with gadolinium injection, then only T1-weighted spin echo sequences after gadolinium injection (0.1 mmol/kg). The mean postoperative follow up period in the 47 patients was 32 months (range 7 to 84 months). Contrast enhancement of the spinal cord was observed in 20 cases. In the 6 patients with recurrence (5 astrocytomas, 1 malignant ependymoma) there was a segmental increase of spinal cord volume with contrast enhancement after gadolinium injection. In 3 out of these 6 patients clinical deterioration appeared later than MRI semiology. In clinically stable patients neither enhancement nor increase in spinal cord size was found in 27 cases, and enhancement alone was noted in 12 cases. There was no reliable criterion in the analysis of post gadolinium signal enhancement that could be used to differentiate recurrence from cicatricial contrast enhancement.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

磁共振成像(MRI)是髓内肿瘤的标准检查方法。对患者进行随访对于早期发现和治疗可能的复发至关重要。本文旨在明确脊髓内胶质瘤术后的MRI影像学特征。在1986年至1992年期间,对47例在比塞特尔医院接受原发性脊髓肿瘤手术的患者进行了高场强MR(1.5特斯拉,GE公司的Signa)随访。由两位神经放射科医生进行回顾性视觉研究。患者组包括24名女性和23名男性,年龄在15至67岁之间(平均38岁)。所治疗的肿瘤包括29例室管膜瘤和18例星形细胞瘤。分析了85次MRI检查。大多数检查至少包括T1加权和T2加权自旋回波序列的两个平面,并注射钆剂,然后仅在注射钆剂(0.1 mmol/kg)后进行T1加权自旋回波序列检查。47例患者的平均术后随访期为32个月(范围为7至84个月)。2例观察到脊髓有强化。在6例复发患者(5例星形细胞瘤,1例恶性室管膜瘤)中,钆剂注射后脊髓体积节段性增加并伴有强化。在这6例患者中的3例中,临床恶化出现晚于MRI影像学表现。在临床稳定的患者中,27例未发现强化或脊髓大小增加,12例仅发现强化。在分析钆剂注射后的信号强化时,没有可靠的标准可用于区分复发与瘢痕性强化。(摘要截短于250字)

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