Robathan G, Woodger S, Merante D
J Intraven Nurs. 1995 Mar-Apr;18(2):84-7.
The use of total parenteral nutrition (TPN) has increased considerably in recent years, resulting in greater demands on human and material resources. Current practice in most hospitals is to replace i.v. lines for TPN every 24 hours, whereas all other i.v. lines are changed every 72 hours. A prospective study was conducted in a pediatric hospital to compare the nosocomial infection incidence between 24- and 72-hour TPN line changes. The convenience sample of 279 patients receiving TPN was studied over two consecutive 12-month periods. A statistically significant decrease was found in the incidence of nosocomial septicemia in the 72 hour line change group. A substantial decrease also was demonstrated in the overall cost of TPN management.
近年来，全胃肠外营养（TPN）的使用显著增加，这对人力和物力资源提出了更高的要求。大多数医院目前的做法是每24小时更换一次TPN的静脉输液管，而其他所有静脉输液管则每72小时更换一次。一家儿科医院进行了一项前瞻性研究，以比较24小时和72小时更换TPN输液管时的医院感染发生率。对279例接受TPN治疗的患者进行了连续两个12个月周期的便利抽样研究。结果发现，72小时更换输液管组的医院败血症发生率有统计学意义的下降。TPN管理的总体成本也有大幅下降。
