Hallfeldt K, Dornschneider G, Richter C, Thetter O, Schweiberer L
Chirurgische Klinik, Klinikum Innenstadt, Ludwig-Maximilians-Universität München, Germany.
Langenbecks Arch Chir. 1995;380(1):37-42. doi: 10.1007/BF00184414.
The quality of perioperative treatment for patients undergoing thoracic surgery is of the utmost importance for postoperative morbidity and mortality. Hence, it was the purpose of this study to examine various aspects of our own procedure. The clinical course following 812 successive thoracotomies in 792 patients over a period of 3 years was documented and analysed. The overall complication rate was found to be 19.7%, with a mortality of 3.8% over a 30-day period. Secretostasis, atelectasis and pneumonia were the most common complications. Owing to the predeposition of autologous blood, the percentage of patients requiring allogeneic blood transfusion was reduced from 27% to 9%. There was no evidence suggesting an increase in the complication rate or a longer stay in hospital. Perioperative antibiotic prophylaxis has reduced postoperative wound infection significantly. Similar reductions in the FEV1 are recorded following thoracic surgery, irrespective of the amount of lung tissue resected. This observation indicates that the remaining lung tissue is severely compromised throughout the postoperative period and that the surgical trauma alone is a major factor influencing postoperative pulmonary function for at least 2 weeks.
胸外科手术患者围手术期治疗的质量对于术后发病率和死亡率至关重要。因此,本研究旨在探讨我们自身手术过程的各个方面。记录并分析了792例患者在3年期间连续进行的812次开胸手术的临床过程。发现总体并发症发生率为19.7%,30天内死亡率为3.8%。分泌物潴留、肺不张和肺炎是最常见的并发症。由于自体血预存,需要异体输血的患者比例从27%降至9%。没有证据表明并发症发生率增加或住院时间延长。围手术期抗生素预防显著降低了术后伤口感染。无论切除的肺组织量如何,胸外科手术后第一秒用力呼气量(FEV1)都会出现类似程度的下降。这一观察结果表明,术后剩余肺组织在整个术后期间受到严重损害,而且仅手术创伤就是影响术后肺功能至少2周的主要因素。