大鼠伏隔核核心区和壳区胆碱能神经元中编码多巴胺D1或D2受体的mRNA的差异定位。
Differential localization of mRNAs encoding dopamine D1 or D2 receptors in cholinergic neurons in the core and shell of the rat nucleus accumbens.
作者信息
Jongen-Rêlo A L, Docter G J, Jonker A J, Voorn P
机构信息
Graduate School of Neurosciences Amsterdam, Vrije Universiteit, Faculty of Medicine, Department of Anatomy and Embryology, The Netherlands.
出版信息
Brain Res Mol Brain Res. 1995 Jan;28(1):169-74. doi: 10.1016/0169-328x(94)00239-b.
By combining immunocytochemistry for ChAT and in situ hybridization for dopamine D1 or D2 receptor mRNA in the striatum, it was found that (1) the percentage of ChAT/D2 mRNA co-localization is higher in the caudate-putamen than in the shell and core of the nucleus accumbens, (2) in the shell the degree of ChAT/D2 mRNA co-localization is higher rostrally than caudally, and 3) no significant regional differences exist in the degree of co-localization of ChAT and D1 mRNA.
通过将纹状体中胆碱乙酰转移酶（ChAT）的免疫细胞化学与多巴胺D1或D2受体mRNA的原位杂交相结合，发现：（1）尾状核-壳核中ChAT/D2 mRNA共定位的百分比高于伏隔核的壳和核心；（2）在壳中，ChAT/D2 mRNA共定位程度在嘴侧高于尾侧；（3）ChAT和D1 mRNA共定位程度不存在显著的区域差异。
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