Nanni G, Gangeri G, Magalini S C, Grieco A, Piantelli M
Istituto di Clinica Chirurgica, Università Cattolica del Sacro Cuore, Roma.
Minerva Chir. 1994 Nov;49(11):1165-70.
A 78-year old male came to our observation presenting and enlargement of bilateral inguinal lymph nodes and a tumor of the mesogastric abdominal wall. Three years before the patient had been operated on for a primary tumor of the umbilicus with concomitant longstanding diarrhea. No histological examination was performed at that time. We performed a lymph node biopsy which demonstrated carcinoid metastasis. We went on to perform radical resection of the abdominal wall, regional lymphadenectomy and right hemicolectomy for malignant villous adenoma of the right colon. The abdominal defect was repaired by using Goretex mesh. Cyclic adjuvant alpha-interferon therapy was continued for more than 1 year, followed by long term therapy with longastatin. Twenty months after the operation the patient is in good clinical conditions and disease-free. On the basis of literature review our case appears to be the first primary carcinoid of the umbilicus.
一名78岁男性前来我院就诊，表现为双侧腹股沟淋巴结肿大及中腹部腹壁肿瘤。三年前，该患者因脐部原发性肿瘤伴长期腹泻接受手术治疗。当时未进行组织学检查。我们进行了淋巴结活检，结果显示为类癌转移。随后，我们对患者进行了腹壁根治性切除术、区域淋巴结清扫术及右半结肠恶性绒毛状腺瘤切除术。腹部缺损采用戈尔泰克斯补片修复。患者持续接受了1年多的周期性辅助α-干扰素治疗，随后长期使用洛伐他汀治疗。术后20个月，患者临床状况良好，无疾病复发。根据文献回顾，我们的病例似乎是首例脐部原发性类癌。
