Iigo M, Kezuka H, Suzuki T, Tabata M, Aida K
Department of Anatomy, St. Marianna University School of Medicine, Kawasaki, Japan.
Neurosci Biobehav Rev. 1994 Winter;18(4):563-9. doi: 10.1016/0149-7634(94)90012-4.
Generation and reception of melatonin signals in the goldfish, Carassius auratus, are reviewed. The photoreceptive pineal gland of the goldfish generates circulating melatonin rhythms according to a given photoperiod under light-dark cycles and in a circadian manner under continuous dark conditions. Melatonin is also produced in the retina in a similar fashion. Melatonin produced in the pineal gland and retina is considered to act as internal zeitgeber in the brain and retina, respectively, controlling various physiological events via specific melatonin binding sites that are coupled with G protein. The goldfish exhibit clear diurnal locomotor activity rhythms under light-dark cycles and free-running rhythms under constant conditions. However, the relationship between melatonin and locomotor activity rhythms in the goldfish remains unclear. Further studies should be required to demonstrate the roles of melatonin in the circadian system in this species.
本文综述了金鱼（Carassius auratus）中褪黑素信号的产生与接收。金鱼的光感受性松果体在明暗循环条件下根据特定光周期产生循环性褪黑素节律，在持续黑暗条件下以昼夜节律方式产生。视网膜也以类似方式产生褪黑素。松果体和视网膜产生的褪黑素分别被认为在大脑和视网膜中充当内部生物钟，通过与G蛋白偶联的特定褪黑素结合位点控制各种生理活动。金鱼在明暗循环条件下表现出明显的昼夜运动活动节律，在恒定条件下表现出自由运行节律。然而，金鱼中褪黑素与运动活动节律之间的关系仍不清楚。需要进一步研究以证明褪黑素在该物种昼夜节律系统中的作用。
