Poplinskaia V A
Ontogenez. 1995 Jan-Feb;26(1):5-21.
This paper is a review discussing the cytomolecular structure of the rods, retinal photoreceptor cells, whose structural uniformity contributed to the progress in studies of their structure and morphogenesis in the vertebrate eye. Recent studies of protein and phospholipid metabolism in the rod inner segment have been reviewed. The structure of the outer segment connecting cilium is discussed with reference to the TEM and SEM, freeze-fracture, biochemical and immunological studies. The membranes of the rod outer segment undergo continuous renewal. The use of fine biochemical methods permitted to find differences in the structure of the plasma membrane surrounding the rod outer segment and the membrane discs, that fill this segment. Recent hypotheses dealing with morphogenesis of the rod outer segment membrane discs are also discussed. Special attention is paid to actin and myosin, as well as a small transient fraction of galactose-containing rhodopsin.
本文是一篇综述，讨论了视杆细胞（视网膜光感受器细胞）的细胞分子结构，其结构的一致性推动了脊椎动物眼中视杆细胞结构及其形态发生研究的进展。本文综述了视杆细胞内段蛋白质和磷脂代谢的最新研究。结合透射电子显微镜（TEM）和扫描电子显微镜（SEM）、冷冻断裂、生化及免疫学研究，对视杆细胞外段连接纤毛的结构进行了讨论。视杆细胞外段的膜不断更新。运用精细的生化方法得以发现围绕视杆细胞外段的质膜与填充该段的膜盘在结构上的差异。本文还讨论了有关视杆细胞外段膜盘形态发生的最新假说。特别关注了肌动蛋白和肌球蛋白，以及一小部分含半乳糖的瞬时视紫红质。
