Andersen O, Zweidorff O K, Hjelde T, Rødland E A
Sola legesenter.
Tidsskr Nor Laegeforen. 1995 Mar 20;115(8):947-9.
Dysphagia, or difficulty in swallowing tablets, may greatly affect compliance. This report presents the results of our survey, which was undertaken to determine the proportion of a general practitioner's patient population who had difficulty in swallowing tablets, and to identify the reasons for the difficulty. 6,158 questionnaires were received from patients who consulted a general practitioner. More than 1/4 (26%) of the total patient population (or 1,576) said they had problems in swallowing tablets. A prominent complaint was the size of the tablet, followed by the surface, form and taste of the tablet. Twice as many women as men experienced swallowing problems. Elderly patients (> 70 years) had less difficulty than younger patients when taking tablets. To achieve good compliance and optimal pharmacotherapy, it is important for medical practitioners and pharmaceutical personnel to be aware of the general problems connected to swallowing tablets, to enable them to select the correctly formulated drug for their patients. New and novel oral drug formulations, such as tablets that dissolve in seconds on the tongue without water, may alleviate the problem of swallowing tablets. They offer substantial advantages over ordinary tablets, are more convenient to administer, and enhance the potential for improved compliance in patients who experience difficulty in taking tablets.
吞咽困难，即吞服片剂困难，可能会极大地影响依从性。本报告展示了我们的调查结果，该调查旨在确定全科医生患者群体中吞服片剂困难的比例，并找出困难的原因。我们收到了6158份向全科医生咨询的患者问卷。超过四分之一（26%）的患者群体（即1576人）表示他们在吞服片剂方面存在问题。一个突出的抱怨是片剂的大小，其次是片剂的表面、形状和味道。经历吞咽问题的女性人数是男性的两倍。老年患者（>70岁）在服用片剂时比年轻患者困难更少。为了实现良好的依从性和最佳药物治疗，医生和制药人员了解与吞服片剂相关的常见问题非常重要，以便他们为患者选择配方正确的药物。新型口服药物制剂，如无需用水就能在舌头上几秒内溶解的片剂，可能会缓解吞服片剂的问题。它们比普通片剂具有显著优势，给药更方便，并提高了片剂服用困难患者改善依从性的可能性。
