Steffensen G K, Pachaï A, Pedersen S E
Børneafdelingen, Aalborg Sygehus Nord.
Ugeskr Laeger. 1998 Apr 6;160(15):2249-52.
Children's compliance with orally administered medicine is described. Five hundred questionnaires were given to the parents of children at their first visit at the out-patient clinic with a response from 484. Three hundred and ninety-seven children had been treated with oral medication in the form of liquid formulation or tablets, 257 within the previous year. Of these, 43.2% reported difficulties in taking the medication. Only 8.5% of the treatments had been interrupted. The main cause of the problems were the medications' taste and difficulties with swallowing tablets. The problems were more pronounced among the younger children. The administration of tablets was more difficult than the administration of liquids. There was no relationship between the problems and frequency of dosing, duration of treatment, severity of illness, social status of the parents, or the parents' age. In conclusion, prescription of better tasting mixtures and chewable tablets may reduce the problems associated with administering oral medication to children.
本文描述了儿童口服药物的依从性情况。研究向首次到门诊就诊儿童的家长发放了500份问卷，收到484份回复。397名儿童曾接受过液体制剂或片剂形式的口服药物治疗，其中257名儿童在过去一年中接受过治疗。在这些儿童中，43.2%的家长报告孩子服药存在困难。只有8.5%的治疗过程被中断。问题的主要原因是药物的味道以及吞咽片剂困难。这些问题在年幼儿童中更为明显。服用片剂比服用液体制剂更困难。这些问题与给药频率、治疗持续时间、疾病严重程度、家长社会地位或家长年龄之间没有关联。总之，开具味道更好的合剂和咀嚼片可能会减少给儿童口服给药相关的问题。
