Zubov A N, Pisareva L N, Semenova S B
Tsitologiia. 1994;36(11):1091-101.
In rat peritoneal macrophages the patch-clamp technique in whole-cell configuration was used to study modifications of membrane potential as a result of extracellular application of micromolar ATP concentration. The registered changes in membrane potential appeared to be of different form and polarization depending on the presence of Ca2+ in extracellular solution and on the concentration of calcium buffer inside the cell. A mechanism of membrane potential changes and their possible connection with the generation of a Ca2+ signal in the cell are discussed.
在大鼠腹膜巨噬细胞中，采用全细胞模式的膜片钳技术来研究细胞外施加微摩尔浓度ATP后膜电位的变化。根据细胞外溶液中Ca2+的存在情况以及细胞内钙缓冲液的浓度，记录到的膜电位变化呈现出不同的形式和极化状态。本文讨论了膜电位变化的机制及其与细胞内Ca2+信号产生的可能联系。
