Guadagnoli E, Ayanian J Z, Gibbons G, McNeil B J, LoGerfo F W
Department of Health Care Policy, Harvard Medical School, Boston, Mass., USA.
Arch Surg. 1995 Apr;130(4):381-6. doi: 10.1001/archsurg.1995.01430040043006.
To assess whether rates of amputation and leg-sparing surgery for peripheral vascular disease of the lower extremities differ between African-American and white patients.
Retrospective cohort study using Medicare claims data for 1989 and 1990.
A total of 3313 hospitals in the United States.
Random sample of 19,236 Medicare Part A enrollees who underwent amputation and/or leg-sparing surgery for peripheral vascular disease.
Adjusted odds of toe and/or foot amputation, below-knee amputation, above-knee amputation, lower extremity arterial vascularization, and percutaneous transluminal angioplasty for African American relative to whites, controlling for case-mix, region, and hospital characteristics.
African-American patients were significantly more likely than white patients to undergo above-knee, below-knee, and toe and/or foot amputation and significantly less likely to undergo lower-extremity arterial revascularization and percutaneous transluminal angioplasty. These associations occurred for diabetic patients and nondiabetic patients but were more pronounced among patients who did not have diabetes.
Potential explanations include unmeasured factors such as severity of disease and the technical expertise available at hospitals or other factors such as lack of compliance with medical treatment and race-specific treatment decisions by providers. Whatever the cause, interventions aimed toward reducing the number of amputations among African Americans are needed. Further work is required to determine where such interventions should be targeted.
评估非裔美国患者与白人患者在下肢外周血管疾病的截肢率和保肢手术率上是否存在差异。
利用1989年和1990年医疗保险理赔数据进行的回顾性队列研究。
美国总共3313家医院。
从19236名因外周血管疾病接受截肢和/或保肢手术的医疗保险A部分参保人中随机抽取的样本。
相对于白人,非裔美国人进行趾和/或足部截肢、膝下截肢、膝上截肢、下肢动脉血管重建以及经皮腔内血管成形术的校正比值比,同时控制病例组合、地区和医院特征。
非裔美国患者比白人患者更有可能接受膝上、膝下以及趾和/或足部截肢,而接受下肢动脉血运重建和经皮腔内血管成形术的可能性则显著更低。这些关联在糖尿病患者和非糖尿病患者中均存在,但在非糖尿病患者中更为明显。
可能的解释包括一些未测量的因素,如疾病严重程度和医院现有的技术专长,或其他因素,如不遵守医疗治疗以及医疗服务提供者的种族特异性治疗决策。无论原因是什么,都需要采取旨在减少非裔美国人截肢数量的干预措施。还需要进一步开展工作来确定此类干预措施的目标对象。