Mitra S C, Ganesh V, Apuzzio J J
Department of Obstetrics and Gynecology, UMDNJ-New Jersey Medical School, Newark, USA.
Am J Perinatol. 1995 Jan;12(1):11-3. doi: 10.1055/s-2007-994389.
The object of this study was to determine if a correlation exists between the resistance index (RI) of the umbilical artery, the RI of the fetal renal artery, and hourly urine output by fetuses of normal pregnancies. Doppler flow study of the fetal renal artery and the umbilical artery was performed in 110 fetuses between 19 and 40 weeks' gestation. Color and pulse wave Doppler was used to obtain the flow velocity waveforms. The RI of the flow velocity waveforms was calculated. Fetal bladder volume was calculated by transverse, anteroposterior, and longitudinal diameters obtained from coronal and transverse sonographic images of the fetal urinary bladder. The difference in bladder volume at 30-minute intervals was used to determine hourly urine output. Gestational age has a positive linear association with fetal urine output (P < 0.01). The RI of the fetal renal artery has a negative linear association with gestational age (P < 0.05). The RI of the umbilical artery decreased with an increase in gestation age (P < 0.01). There was a significant correlation between the RI of the umbilical artery (P < 0.01) and the fetal renal artery (P < 0.05) and hourly urine output by the fetus. The RI of the fetal renal artery decreased with gestational age. Hourly urine output of the fetus increased with gestational age. The RI of the umbilical artery and the fetal renal artery had a significant correlation with fetal urine output.
本研究的目的是确定正常妊娠胎儿的脐动脉阻力指数（RI）、胎儿肾动脉RI与每小时尿量之间是否存在相关性。对110例孕19至40周的胎儿进行了胎儿肾动脉和脐动脉的多普勒血流研究。采用彩色和脉冲波多普勒获取血流速度波形。计算血流速度波形的RI。通过从胎儿膀胱的冠状和横向超声图像获得的横径、前后径和纵径计算胎儿膀胱体积。以30分钟间隔的膀胱体积差异来确定每小时尿量。孕周与胎儿尿量呈正线性相关（P<0.01）。胎儿肾动脉RI与孕周呈负线性相关（P<0.05）。脐动脉RI随孕周增加而降低（P<0.01）。脐动脉RI（P<0.01）和胎儿肾动脉RI（P<0.05）与胎儿每小时尿量之间存在显著相关性。胎儿肾动脉RI随孕周增加而降低。胎儿每小时尿量随孕周增加而增加。脐动脉RI和胎儿肾动脉RI与胎儿尿量存在显著相关性。
