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[嗅觉诱发电位和关联性负变在嗅觉障碍专家评估中的应用]

[Olfactory evoked potentials and contingent negative variation in expert assessment of disordered sense of smell].

作者信息

Matern G, Matthias C, Mrowinski D

机构信息

Hals-Nasen-Ohren-Universitätsklinik im Klinikum Rudolf Virchow.

出版信息

Laryngorhinootologie. 1995 Feb;74(2):118-21. doi: 10.1055/s-2007-997702.

DOI:10.1055/s-2007-997702
PMID:7710604
Abstract

Normally, the sense of smell is assessed by means of traditional subjective tests (sniff test, gustatory smell test, and trigeminus test). When results are inconclusive, an objective smell test is indicated. Simultaneously registering olfactory evoked potentials (OEP) and contingent negative variation (CNV) permits evaluation of both odor perception and odor discrimination. We can even objectively assess the false olfactory sensations in parosmia patients who are unable to discriminate between different odors. In this study, the results of 59 patients with olfactory disorders are presented. Head trauma and upper respiratory infections were the most common causes of the patients' complaints. In twelve cases, lack of cooperation and patient unrest prevented us from evaluating the data. In anosmia, the objective results agreed completely with the patient's subjective assessment. In hyposmia and parosmia, the results agreed with the patient's subjective assessment in most cases; here we were able to arrive at a more specific diagnosis in several cases. The objective smell test can be used to supplement subjective methods and thus provide more reliable assessment of olfactory disorders.

摘要

通常,嗅觉是通过传统的主观测试(嗅觉测试、味觉嗅觉测试和三叉神经测试)来评估的。当结果不明确时,就需要进行客观嗅觉测试。同时记录嗅觉诱发电位(OEP)和伴随负变化(CNV)可以评估气味感知和气味辨别能力。我们甚至可以客观地评估嗅觉倒错患者无法区分不同气味时的假性嗅觉感受。在本研究中,展示了59例嗅觉障碍患者的结果。头部外伤和上呼吸道感染是患者主诉的最常见原因。在12例中,患者缺乏合作及躁动不安使我们无法评估数据。在嗅觉丧失患者中,客观结果与患者的主观评估完全一致。在嗅觉减退和嗅觉倒错患者中,多数情况下结果与患者的主观评估相符;在一些病例中我们能够得出更具体的诊断。客观嗅觉测试可用于补充主观方法,从而为嗅觉障碍提供更可靠的评估。

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