生物微量元素研究中断层扫描方法的进展。

Developments in tomographic methods for biological trace element research.

作者信息

Spyrou N M, Sharaf J M, Rajeswaran S

机构信息

Department of Physics, University of Surrey, Guildford, UK.

出版信息

Biol Trace Elem Res. 1994 Fall;43-45:55-63. doi: 10.1007/BF02917299.

DOI:10.1007/BF02917299

PMID:7710873

Abstract

Neutron-induced gamma-ray emission tomography for quantitative determination of concentration and distribution of elements in a selected plane through a biological specimen is briefly explained and applied by way of illustration to the analysis of gallstones. A system capable of carrying out studies of the binding site of 75Se is different matrices using time differential perturbed angular correlation spectroscopy is also briefly described. Developments in the detector technology of positron emission tomography have allowed small-diameter imaging devices to be built for in vivo preclinical evaluation of new tracers in small animals and are discussed in the context of a proposed experiment combining the techniques mentioned above.

摘要

简要解释了用于通过生物样本定量测定选定平面中元素浓度和分布的中子诱导γ射线发射断层扫描技术，并通过胆结石分析进行了举例应用。还简要描述了一种能够使用时间微分扰动角关联光谱学对不同基质中75Se结合位点进行研究的系统。正电子发射断层扫描探测器技术的发展使得能够制造小直径成像设备，用于小动物体内新示踪剂的临床前评估，并在结合上述技术的拟议实验背景下进行了讨论。