Carney J A
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Dermatol Clin. 1995 Jan;13(1):19-26.
The Carney complex is a multisystem tumorous disorder that features myxomas (heart, skin, and breast), spotty skin pigmentation (lentigines and blue nevi), endocrine tumors (adrenal, testicular, and pituitary), and peripheral nerve tumors (schwannomas). The condition is transmitted as an autosomal dominant trait. The most serious components of the syndrome are cardiac myxoma and psammomatous melanotic schwannoma. The cutaneous manifestations are a major clue to the disorder.
卡尼综合征是一种多系统肿瘤性疾病,其特征包括黏液瘤(心脏、皮肤和乳腺)、散在性皮肤色素沉着(雀斑和蓝痣)、内分泌肿瘤(肾上腺、睾丸和垂体)以及周围神经肿瘤(神经鞘瘤)。该病症以常染色体显性性状遗传。该综合征最严重的组成部分是心脏黏液瘤和砂粒性黑素性神经鞘瘤。皮肤表现是该疾病的主要线索。