Theegarten D, Sardisong F, Philippou S
Abteilung für Pathologie, Ruhr-Universität Bochum.
Chirurg. 1995 Feb;66(2):158-61.
Up to now 8 cases of malignant fibrous histiocytoma are reported in whom the tumor had developed after total hip replacement. Direct contact between tumor and prosthesis was proved in 7 cases. We report on a female patient of 74 years of age in whom a malignant fibrous histiocytoma of the gluteal region had formed 15 years after total hip replacement. Tumor was located in the old operation scar. Not only a direct effect of the foreign material, but also the scar has to be regarded as an etiological factor in pathogenesis of malignant fibrous histiocytoma in these cases.