Zheng L M, Wang J Z
Tianjin Medical University.
Zhonghua Nei Ke Za Zhi. 1994 Oct;33(10):658-60.
Iatrogenic osteoporosis is a very common secondary osteoporosis is found in patients treated with large dosage of glucocorticosteroid of long duration. Six cases listed in this article including 2 cases of bronchial asthma, 2 cases of bronchial asthma, 2 cases of rheumatoid arthritis, 1 case of skin disease and 1 case of callagenosis (three male patients and three female patients). The age is from 27-46. The duration of treatment of primary disease with glucocorticosteroid is 1 to 3.5 years, with the average of 1.56 years. With the exception of one case treated with Dexamethasone one of 0.75g daily, the other 5 cases are treated with predinisone of 5-30mg daily. After they treated with hormone every other day and added Calcium and vitamin D and followed up 1 year, the mineral contents in the bone of all 6 patients are increased and the biochemistry indexes are improved.
医源性骨质疏松是一种非常常见的继发性骨质疏松，见于长期大剂量使用糖皮质激素治疗的患者。本文列举6例，其中支气管哮喘2例、类风湿关节炎2例、皮肤病1例、胶原病1例（男性3例，女性3例）。年龄27至46岁。原发性疾病使用糖皮质激素治疗的疗程为1至3.5年，平均1.56年。除1例每日服用0.75g地塞米松外，其他5例每日服用泼尼松5至30mg。在他们隔日使用激素并补充钙和维生素D并随访1年后，所有6例患者的骨矿物质含量均增加，生化指标得到改善。
