丰富的个人经验：促性腺激素腺瘤。

Extensive personal experience: gonadotroph adenomas.

作者信息

Snyder P J

机构信息

Division of Endocrinology, Metabolism and Diabetes, University of Pennsylvania School of Medicine, Philadelphia 19104-6149, USA.

出版信息

J Clin Endocrinol Metab. 1995 Apr;80(4):1059-61. doi: 10.1210/jcem.80.4.7714066.

DOI:10.1210/jcem.80.4.7714066

PMID:7714066

Abstract

Our experience with gonadotroph adenomas during the last 20 years has taught us how to recognize them by their size, neurologic symptoms, and inefficient and incomplete secretion of intact gonadotropins and their subunits. Treatment now is primarily by transsphenoidal surgery and secondarily by radiation. Future development of a pharmacologic treatment will likely await more detailed knowledge of their pathogenesis.

摘要

我们在过去20年中对促性腺激素腺瘤的经验告诉我们，如何通过其大小、神经症状以及完整促性腺激素及其亚基的分泌低效和不完全来识别它们。目前的治疗主要是经蝶窦手术，其次是放疗。药物治疗的未来发展可能需要等待对其发病机制有更详细的了解。