Uryu K
Department of Surgery, Tokyo Medical College, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1995 Feb;43(2):168-73.
The purpose of this introducing study was to establish the normal lung density using computed tomography of the chest. If it is possible to analyze the density of normal lung parenchyma, it could be possible to estimate the quantity of effective ventilation capacity based on account of the CT number of given range. A cross section of the lung, however, is not homogeneous because it contents of vascular tissue, interstitial tissue, air and others which have widely variety densities. To estimate pulmonary function, it is necessary to know the exact CT number of only normal lung tissue. Mean values for varies tissues and areas in the thorax were assessed in 34 patients (21 males, 13 females, average age: 58 years, from August 1987 to June 1993), 18 case of lung cancer (10 preoperative, 8 postoperative), 5 metastatic lung cancer, 1 giant bulla, 1 aspergilloma, 1 pulmonary AV fistula, 8 case had no lung disease. The measured normal peripheral lung by radiographic appearance on CT images, vascular in the lung, bronchus, rib, muscle and fat structured chest wall, heart, liver, aorta, esophagus, and thymus. Density of normal peripheral lung tissue was measured in 6 points on each slices. These scores were compared left vs. right, slice number, and anterior vs. posterior. The CT numbers in this study following the no enhanced computed tomography scanner: GE9800 CT by using the regions of interest which limited in 0.01 cm 2 area. There was no significant difference between left and right lung, among different slices, although between anterior and posterior in the normal lung.(ABSTRACT TRUNCATED AT 250 WORDS)
这项引入性研究的目的是通过胸部计算机断层扫描确定正常肺密度。如果能够分析正常肺实质的密度,那么基于给定范围内的CT值就有可能估计有效通气量。然而,肺的横截面并不均匀,因为它包含血管组织、间质组织、空气等,其密度差异很大。为了评估肺功能,有必要知道仅正常肺组织的确切CT值。对34例患者(21例男性,13例女性,平均年龄58岁,时间从1987年8月至1993年6月)的胸部不同组织和区域的平均值进行了评估,其中18例肺癌患者(10例术前,8例术后),5例肺转移癌,1例巨大肺大疱,1例曲菌球,1例肺动静脉瘘,8例无肺部疾病。通过CT图像上的影像学表现测量正常外周肺、肺内血管、支气管、肋骨、构成胸壁的肌肉和脂肪、心脏、肝脏、主动脉、食管和胸腺。在每个切片上的6个点测量正常外周肺组织的密度。比较这些得分的左右差异、切片编号差异以及前后差异。本研究中的CT值是在未增强的计算机断层扫描仪(GE9800 CT)上使用面积限制在0.01平方厘米的感兴趣区域测得的。正常肺的左右肺之间、不同切片之间没有显著差异,尽管正常肺的前后之间存在差异。(摘要截断于250字)