[新生霉素对左菌素和左菌素他汀产生菌——左旋放线菌的选择性作用]

[Selective action of novobiocin on Act. levoris, the producer of levorin and levoristatin].

作者信息

Lanskaia L N, Zhukova R A

出版信息

Antibiotiki. 1978 Apr;23(4):295-8.

PMID:77146

Abstract

The effect of sodium novobiocin on Act. levoris, strain LIA 0868 producing levorin and levoristatin was studied. High lethal effect of the antibiotic on Act. levoris was found. The effect increased with a rise in the antibiotic concentration in the agar from 2 to 6 lambda/ml. The inhibitory effect of novobiocin on Act, levoris was evident from a marked increase in the number of morphologically changed colonies with a low level of levorin production. The selective effect of novobiocin on the organism producing levorin and levoristatin was evident from selection of variants with high levels of levoristatin production on media containing novobiocin.

摘要

研究了新生霉素钠对产生左菌素和左菌素他汀的左旋放线菌LIA 0868菌株的作用。发现该抗生素对左旋放线菌有很高的致死作用。随着琼脂中抗生素浓度从2微克/毫升增加到6微克/毫升，这种作用增强。新生霉素对左旋放线菌的抑制作用从形态改变的菌落数量显著增加以及左菌素产生水平较低中明显可见。新生霉素对产生左菌素和左菌素他汀的生物体的选择作用从在含有新生霉素的培养基上选择左菌素他汀产生水平高的变体中明显可见。

相似文献

1

[Selective action of novobiocin on Act. levoris, the producer of levorin and levoristatin].[新生霉素对左菌素和左菌素他汀产生菌——左旋放线菌的选择性作用]

Antibiotiki. 1978 Apr;23(4):295-8.

2

[Comparative study of the action of streptomycin on the variability of levorin and amphotericin B producers].

Antibiotiki. 1977 May;22(5):396-400.

3

[Action of the products of the vital activity of yeastlike fungi on the biosynthesis of levorin, levoristatin and fatty acids by a Streptomyces levoris culture].[类酵母真菌生命活动产物对左旋链霉菌培养物合成左菌素、左菌素抑制素和脂肪酸的作用]

Antibiotiki. 1984 Jul;29(7):483-7.

4

[Variability of the levorin producer, Actinomyces levoris Krass].[左旋菌素产生菌，左旋放线菌（Krass）的变异性]

Antibiotiki. 1975 Mar;20(3):227-32.

5

[Effect of aromatic amino acids on levorin biosynthesis].[芳香族氨基酸对左菌素生物合成的影响]

Antibiotiki. 1982;27(9):655-8.

6

[Toxic action of the polyene antibiotic levorin on the superproducer Streptomyces levoris].[多烯抗生素左菌素对高产菌株左氏链霉菌的毒性作用]

Antibiot Med Biotekhnol. 1987 Oct;32(10):731-4.

7

[Action of hygromycin B on the producers of levorin and mycoheptin].[潮霉素B对左菌素和抗霉菌素产生菌的作用]

Antibiotiki. 1975 Oct;20(10):880-5.

8

[Effect of inorganic phosphate on levorin biosynthesis and on the mycelial makeup of Streptomyces levoris].[无机磷酸盐对左旋霉素生物合成及左旋链霉菌菌丝组成的影响]

Antibiotiki. 1979 Sep;24(9):656-9.

9

[Dissociation of a Candida tropicalis culture and its capacity to stimulate levorin synthesis when cultured together with Actinomyces levoris].[热带假丝酵母培养物的解离及其与左旋放线菌共同培养时刺激左旋霉素合成的能力]

Antibiotiki. 1978 Mar;23(3):199-203.

10

[The effect of lipase from Penicillium sp. on the membrane fraction of the levorin-producing Streptomyces levoris].

Prikl Biokhim Mikrobiol. 1988 Mar-Apr;24(2):193-5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。