Fujisawa S, Kanamori H, Noguchi T, Maruta A, Ogawa K, Sakai R, Taguchi J, Tomita N, Kodama F, Okubo T
Department of Hematology and Chemotherapy, Kanagawa Cancer Center.
Rinsho Ketsueki. 1995 Jan;36(1):56-8.
A 74-year-old woman was admitted in October 1988 with anemia and leukocytopenia. Hematologic investigations established a diagnosis of hypoplastic acute leukemia. She received a low dose of cytosine arabinoside (LDAC: 10 mg/m2 every 12 hours) subcutaneously for 21 days and achieved complete remission (CR) one month later. After one course of LDAC of 14 days, she received LDAC of 21 days every 5 to 6 months as maintenance therapy till April 1993. She has been in remission for 6 years. Intensification therapy with LDAC every 5 to 6 months might be useful in maintaining remission for hypoplastic acute leukemia.
一名74岁女性于1988年10月因贫血和白细胞减少入院。血液学检查确诊为再生障碍性急性白血病。她接受了低剂量阿糖胞苷（LDAC：每12小时10mg/m²）皮下注射，共21天，1个月后达到完全缓解（CR）。在一个疗程14天的LDAC治疗后，她每5至6个月接受21天的LDAC作为维持治疗，直至1993年4月。她已缓解6年。每5至6个月用LDAC进行强化治疗可能有助于维持再生障碍性急性白血病的缓解状态。
