Szreter M, Jóźwiak S, Michałowicz R
Oddziału Okulistyki CZD w Warszawie.
Klin Oczna. 1994 Oct-Nov;96(10-11):315-7.
The authors discussed ocular changes observed in 100 children with tuberous sclerosis. Retinal tumors, typical of this disease, were found in 19 patients (19%). This incidence was higher in older children. Three types of tumors were observed: a) flat or slightly elevated, indistinct, salmon-grey colour, b) whitish-yellow, mulberry-like, located in disc area, c) mixed or intermediate. The authors observed 4 stages of tumors' development: changes in distribution of pigment in retina, arising of semitranslucent, salmon-grey tumors, mineralization of tumors-so called intermediate type, mulberry-like type. Progress from one stage to the next one is slow.
作者讨论了100例结节性硬化症患儿的眼部变化。在19例（19%）患者中发现了该疾病典型的视网膜肿瘤。这种发病率在年龄较大的儿童中更高。观察到三种类型的肿瘤：a）扁平或略隆起、边界不清、呈鲑鱼灰色，b）位于视盘区域的黄白色、桑葚样，c）混合型或中间型。作者观察到肿瘤发展的4个阶段：视网膜色素分布改变、半透明鲑鱼灰色肿瘤出现、肿瘤矿化（即所谓的中间型、桑葚样型）。从一个阶段发展到下一个阶段进展缓慢。
