Szymański A, Gierek-Lapińska A, Zyłka B, Sobieraj A, Otrzonsek D
Katedry i Kliniki Okulistyki Slaskiej AM w Katowicach.
Klin Oczna. 1994 Oct-Nov;96(10-11):318-21.
The authors evaluated the efficacy of pharmacological support of trabeculectomy by intraoperative application of mitomycin. It was used in selected cases, those of high risk glaucoma as regards to poor surgical effect, in concentrations 0.2 mg/ml and 0.5 mg/ml. There were 32 eyes with following types of secondary glaucoma: neovascular glaucoma in diabetes, glaucoma in aphakic and pseudophakic eyes and simple glaucoma in the eyes after uneffective trabeculectomy. Normalization of the intraocular pressure was achieved in 21 eyes (65.6%). The 1.5-year follow-up revealed that with higher concentrations of mitomycin normalization of the pressure was more frequent lait there occurred more complications than with lower concentrations. Long-lasting hypotony is a difficult complication.
作者通过术中应用丝裂霉素评估了小梁切除术药物辅助治疗的疗效。它被用于特定病例，即那些手术效果不佳的高危青光眼患者，浓度为0.2毫克/毫升和0.5毫克/毫升。共有32只眼睛患有以下类型的继发性青光眼：糖尿病性新生血管性青光眼、无晶状体和人工晶状体眼青光眼以及小梁切除术后无效的单纯性青光眼。21只眼睛（65.6%）实现了眼压正常化。1.5年的随访显示，丝裂霉素浓度越高，眼压正常化越频繁，但并发症也比低浓度时更多。持续性低眼压是一种棘手的并发症。
