发育过程中大鼠前脑NADPH-黄递酶的表达。

Expression of NADPH-diaphorase in the rat forebrain during development.

作者信息

Samama B, Chateau D, Boehm N

机构信息

Institut d'Histologie, Faculté, de Médecine, Strasbourg, France.

出版信息

Neurosci Lett. 1995 Jan 30;184(3):204-7. doi: 10.1016/0304-3940(94)11207-y.

DOI:10.1016/0304-3940(94)11207-y

PMID:7715847

Abstract

Expression of NADPH-diaphorase (NADPH-d) was studied in the rat telencephalon and diencephalon from embryonic day 15 (E15) to postnatal day 30 (P30). The study has focused on the first appearance of NADPH-d staining in some areas which show high expression during adult life. The time of appearance ranged from E15 to the first days following birth, depending on the location of the cells. In many regions, neuronal processes, when staining appeared, were observed in close relationship with cerebral vessels. A possible role for nitric oxide in brain development should be explored.

摘要

在胚胎第15天（E15）至出生后第30天（P30）的大鼠端脑和间脑中研究了NADPH黄递酶（NADPH-d）的表达。该研究聚焦于某些在成年期高表达区域中NADPH-d染色的首次出现情况。出现时间从E15到出生后的头几天不等，这取决于细胞的位置。在许多区域，当染色出现时，观察到神经元突起与脑血管密切相关。应探讨一氧化氮在脑发育中的可能作用。