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大鼠前额叶皮质中烟酰胺腺嘌呤二核苷酸磷酸二酯酶(NADPH-d)阳性神经元的生后发育

Postnatal development of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) positive neurons in rat prefrontal cortex.

作者信息

Tomić D, Zobundźija M, Meáugorac M

机构信息

Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, University of Zagreb, Croatia.

出版信息

Neurosci Lett. 1994 Apr 11;170(2):217-20. doi: 10.1016/0304-3940(94)90322-0.

DOI:10.1016/0304-3940(94)90322-0
PMID:8058191
Abstract

First nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d)-positive perikarya in rat prefrontal cortex (PFC) are present at birth. On postnatal day (P) 1, there is an increase of NADPH-d-positive neurons in all developing layers of PFC. From P1 to P7, a further increase in the overall number of positive neurons is observed. First laminar and area shifts are noted on P21, while morphological maturation of NADPH-d-positive neurons is finished around P30. In conclusion, the postnatal development of NADPH-d neurons in PFC is in concordance with other developmental events in rat cerebral cortex.

摘要

大鼠前额叶皮质(PFC)中最早的烟酰胺腺嘌呤二核苷酸磷酸黄递酶(NADPH-d)阳性核周体在出生时就已存在。在出生后第1天(P1),PFC所有发育层中的NADPH-d阳性神经元数量增加。从P1到P7,阳性神经元的总数进一步增加。在P21时首次注意到层状和区域变化,而NADPH-d阳性神经元的形态成熟在P30左右完成。总之,PFC中NADPH-d神经元的出生后发育与大鼠大脑皮质中的其他发育事件一致。

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