Figueroa Damián R, Sánchez Fernández L, Benavides Covarrubias E, Villagrana Zesati R
Departamento de Infectología e Immunología, Instituto Nacional de Perinatología, México, DF.
Rev Gastroenterol Mex. 1994 Jul-Sep;59(3):246-53.
The association between viral hepatitis and pregnancy is not common, nevertheless it has been described that hepatitis is the most frequent cause of jaundice in pregnant women. In this article the current knowledge on the perinatal repercussions of the different types of viral hepatitis are reviewed. Hepatitis A is rare during pregnancy and is not associated with perinatal risk. Hepatitis B virus (HBV) can be transmitted transplacentally, 20 per cent of the children infected by this route will develop liver cirrhosis or carcinoma in the adult age, so the infants of HBsAg carrier mothers must be immunized at born. The perinatal transmission of hepatitis C virus has been proved but the repercussion in the fetus or newborn is unknown. Hepatitis D virus can only be transmitted from mother to child together with HBV. Hepatitis E has been associated with a mortality of 10 to 40 per cent in pregnant women.
病毒性肝炎与妊娠之间的关联并不常见,不过,已有描述称肝炎是孕妇黄疸最常见的病因。本文对不同类型病毒性肝炎的围产期影响的现有知识进行了综述。甲型肝炎在孕期罕见,且与围产期风险无关。乙型肝炎病毒(HBV)可经胎盘传播,通过此途径感染的儿童中有20%在成年后会发展为肝硬化或肝癌,因此,HBsAg携带者母亲的婴儿必须在出生时进行免疫接种。丙型肝炎病毒的围产期传播已得到证实,但对胎儿或新生儿的影响尚不清楚。丁型肝炎病毒只能与HBV一起从母亲传播给孩子。戊型肝炎与孕妇10%至40%的死亡率相关。